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title: Product Discontinuation Notice - Seraseq® ctDNA Mutation Mix v2 and Seraseq® ctDNA Reference Material v2
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 RECOMMENDED ACTION: Notify appropriate personnel and transition to alternate products  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­    ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­  

|                         Not rendering correctly? View this email as a web page here.                         SUBJECT: Product Discontinuation Notice - Seraseq® ctDNA Mutation Mix v2 and Seraseq® ctDNA Reference Material v2  RECOMMENDED ACTION: Notify appropriate personnel and transition to alternate products  Dear Valued Customer, Our records indicate that you have purchased one or more of the products listed in Table 1. We are issuing this notification to inform you these products will be discontinued from our portfolio, effective 31 Jan 2027. Please notify the appropriate laboratory/ordering personnel of this upcoming change and refer to Table 2 for the available substitute or replacement products. As a part of our ongoing efforts to improve our offerings, we will be retiring the Seraseq ctDNA v2 products listed in Table 1 following the launch of our upgraded Seraseq ctDNA v4 reference materials outlined in Table 2. ctDNA v4 products are designed to be direct replacements for ctDNA v2 products. They not only include 93 variants across 71 solid tumor genes but also feature 10-fold less background noise than our prior version, delivering superior value and greater confidence in test results at low variant allele frequencies. Table 1: Impacted Products Material Number  Product Description Date of Discontinuation 0710-0144  Seraseq® ctDNA Mutation Mix v2 WT  31 JAN 2027    0710-0139  Seraseq® ctDNA Mutation Mix v2 AF2%  31 JAN 2027    0710-0140  Seraseq® ctDNA Mutation Mix v2 AF1% 31 JAN 2027    0710-0141  Seraseq® ctDNA Mutation Mix v2 AF0.5%  31 JAN 2027    0710-0142  Seraseq® ctDNA Mutation Mix v2 AF0.25%    31 JAN 2027     0710-0143 Seraseq® ctDNA Mutation Mix v2 AF0.125%    31 JAN 2027     0710-0208 Seraseq® ctDNA Reference Material v2 WT   31 JAN 2027    0710-0203  Seraseq® ctDNA Reference Material v2 AF2%   31 JAN 2027     0710-0204 Seraseq® ctDNA Reference Material v2 AF1%   31 JAN 2027     0710-0205  Seraseq® ctDNA Reference Material v2 AF0.5%  31 JAN 2027     0710-0207  Seraseq® ctDNA Reference Material v2 AF0.125%   31 JAN 2027   Table 2: Substitute/Replacement Products Available for Purchase Material Number  Product Description  0710-3101  Seraseq® ctDNA Mutation Mix v4 WT   0710-3100  Seraseq® ctDNA Mutation Mix v4 AF5%   0710-3099  Seraseq® ctDNA Mutation Mix v4 AF0.5%   0710-3097  Seraseq® ctDNA Mutation Mix v4 AF0.1%   0710-3989  Seraseq® ctDNA Reference Material v4 WT   0710-3990  Seraseq® ctDNA Reference Material v4 AF5%   0710-3991  Seraseq® ctDNA Reference Material v4 AF0.5%   0710-3992  Seraseq® ctDNA Reference Material v4 AF0.1%   We will continue to fulfill orders of the legacy products until the official discontinuation date or until our inventory is depleted, whichever occurs first. Furthermore, we remain committed to supporting custom product requests as needed. We greatly appreciate your partnership and understanding as we make this change. For questions or additional support, please contact Customer Service at CDx-info@LGCgroup.com or your LGC sales representative. Thank you,  Praveena Kamineni Associate Product Manager, Oncology Follow Us                         LGC Clinical Diagnostics   lgcclinicaldiagnostics.com  37 Birch St.  Milford,  MA   01757   United States You received this email because you are subscribed to Company Notifications from LGC Clinical Diagnostics. Update your email preferences to choose the types of emails you receive.  Unsubscribe from all future emails  |
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